"We will secure that Republic proclaimed in Easter Week," Mary Lou McDonald vowed at the launch of Brian Stanley's campaign.
The Sinn Féin Vice-President highlighted health.
"We will not content ourselves with a banjaxed, two tier health system. Our policy sets out how we get a first class health system. A service which is free at the point of delivery. We have a plan and a road map for the delivery of a universal health care system which can be achieved over two Dail terms.
"This Government has created private wealth and public squalor. Enda Kenny becomes puce in colour and apopletic with rage with the suggestion that those who have the most should pay more tax. He tells us that we are illiterate for suggesting so, and that it would be a social catastrophe. In the world of Enda Kenny and Joan Burton, it's not a social catastrophe to take medical cards off sick children.
"Sinn Féin believes in a fair taxation system, and that the rich should pay a bit more, ensuring that we all pay our fair share,” she said.
Dep McDonald also touched on 1916.
"If they came back today the leaders of 1916 would be disappointed at how far short we have fallen of the Proclamation. The Proclamation itself is a more radical document now than it was 100 years ago."
"This will be a defining election for Ireland. The divine right of Fine Gael and Fianna Fáil to lead government is no longer in the stars. It is no longer a case of tweedledum or tweedledumber.
"Sinn Féin will be in Government, must be in Government, to change Ireland. Sinn Fein is not the Labour Party. Our commitments will be kept," said the TD